Bioinformatics

COORDINATOR

Casanellas Rius, Marta

CONTACT

School of Mathematics and Statistics (FME)
C/ Pau Gargallo, 14
08028 Barcelona

Tel.: 934 015 861

E-mail: gestio.doctorat.bioinformatica@upc.edu

This doctoral programme builds on and extends existing or planned studies in bioinformatics at the bachelor's level (interuniversity degree) and the master's level (at various universities). The programme is aimed at students who wish to undertake research in this field.

Bioinformatics is a cross-disciplinary field that is experiencing a major expansion, in both academia and the professional sphere (hospitals, the pharmaceutical, biotechnology and agri-food sectors, etc.). It is also a field that has a very strong base in Catalonia. Because bioinformatics is a highly interdisciplinary strategic area with significant transnational potential, one of the institutions involved in the doctoral programme is the Bioinformatics Barcelona Association (BIB), which brings together universities, research centres and companies (www.bioinformaticsbarcelona.eu).

The programme brings together the best experts in the fields that bioinformatics encompasses in a programme that is unique in Catalonia and in a way that is aligned with the objectives of the BIB, thus generating greater synergies between biological and computer sciences. Collaboration with other universities provides us with a clear international vision and enables us to set high quality standards that are shared across institutions. These relationships also facilitate the involvement in the programme of experts from various fields of this highly interdisciplinary area, facilitating more effective coverage of the diverse areas that bioinformatics touches on.

The doctoral programme in Bioinformatics aims to produce graduates who are excellent researchers and who have the knowledge and skills needed to contribute new methods, knowledge and tools that benefit present and future users of bioinformatics. High-level research training in bioinformatics opens up a wide range of career opportunities for graduates in academia and many other sectors.

Rationale for the programme

There is strong demand for professionals with high-level research training in bioinformatics to fill positions in hospitals and pharmaceutical, biotechnology and agri-food companies. The explosion of biological data managed by hospitals and companies (the big data paradigm) and the need to design procedures for the correct interpretation of this data in the context of each institution’s specific objectives are the main drivers of this growing demand for specialists with high-level training in bioinformatics.

Other Universities

Universitat Autònoma de Barcelona

University of Girona

University of Lleida

University of Vic–Central University of Catalonia

Universitat Oberta de Catalunya

Universitat Rovira i Virgili (2021)

University of Barcelona (2021)

General information

Access profile

Students must have adequate knowledge of the concepts and basic tools needed to carry out competitively funded research in the field of bioinformatics. Therefore, the main entry route to the programme is via a research-oriented master's degree in a discipline that is relevant to the field of bioinformatics, and priority will be given to applicants with this background.

There is one alternative entry route. Students who have not completed a master's degree but have completed a bachelor's degree in a discipline relevant to bioinformatics that carries at least 300 ECTS credits but does not include research training credits may be admitted to the programme on the condition that they complete, in their first year, 30 ECTS credits corresponding to subjects included on a master’s degree in bioinformatics taught at one of the universities involved in the programme.

The language of instruction for the programme is English. Students must therefore demonstrate a level of competence in English equivalent to Level B2 (upper intermediate) of the Common European Framework of Reference for Languages. If an applicant cannot provide certification of their level of English, this point will be assessed by the Selection and Progress Review Panel during the admission interview.

Output profile

Doctoral candidates who complete a doctoral degree will have acquired the following competencies, which are needed to carry out quality research (Royal Decree 99/2011, of 28 January, which regulates official doctoral studies):

a) A systematic understanding of the field of study and a mastery of the research skills and methods related to the field.
b) An ability to conceive, design or create, put into practice and adopt a substantial process of research or creation.
c) An ability to contribute to pushing back the frontiers of knowledge through original research.
d) A capacity for critical analysis and an ability to assess and summarise new and complex ideas.
e) An ability to communicate with the academic and scientific community and with society in general as regards their fields of knowledge in the manner and languages that are typical of the international scientific community to which they belong.
f) An ability to foster scientific, technological, social, artistic and cultural progress in academic and professional contexts within a knowledge-based society.

The award of a doctoral degree must equip the graduate for work in a variety of settings, especially those requiring creativity and innovation. Doctoral graduates must have at least acquired the personal skills needed to:

a) Develop in contexts in which there is little specific information.
b) Find the key questions that must be answered to solve a complex problem.
c) Design, create, develop and undertake original, innovative projects in their field.
d) Work as part of a team and independently in an international or multidisciplinary context.
e) Integrate knowledge, deal with complexity and make judgements with limited information.
f) Offer criticism on and intellectually defend solutions.

Number of places

8

Duration of studies and dedication regime

Duration
The maximum period of study for full-time doctoral studies is four years, counted from the date of first enrolment in the relevant programme until the date on which the doctoral thesis is deposited. The academic committee of the doctoral programme may authorise a doctoral candidate to pursue doctoral studies on a part-time basis. In this case, the maximum period of study is seven years from the date of first enrolment in the programme until the date on which the doctoral thesis is deposited. To calculate these periods, the date of deposit is considered to be the date on which the thesis is made publicly available for review.

If a doctoral candidate has a degree of disability equal to or greater than 33%, the maximum period of study is six years for full-time students and nine years for part-time students.

For full-time doctoral candidates, the minimum period of study is two years, counted from the date of an applicant's admission to the programme until the date on which the doctoral thesis is deposited; for part-time doctoral candidates it is four years.

When there are justified grounds for doing so, and the thesis supervisor and academic tutor have given their authorisation, doctoral candidates may request that the academic committee of their doctoral programme exempt them from the requirement to complete this minimum period of study.

Temporary disability leave and leave for the birth of a child, adoption or fostering for the purposes of adoption, temporary foster care, risk during pregnancy or infant feeding, gender violence and any other situation provided for in current regulations do not count towards these periods. Students who find themselves in any of these circumstances must notify the academic committee of the doctoral programme, which must inform the Doctoral School.

Doctoral candidates may request periods of temporary withdrawal from the programme for up to a total of two years. Requests must be justified and addressed to the academic committee responsible for the programme, which will decide whether or not to grant the candidate's request.

Extension of studies
If a doctoral candidate has not applied to deposit their thesis before the expiry of the deadlines specified in the previous section, the academic committee of the doctoral programme may, at the request of the doctoral candidate, authorise an extension of this deadline of one year under the conditions specified for the doctoral programme in question.

Dismissal from the doctoral programme
A doctoral candidate may be dismissed from a doctoral programme for the following reasons:

  • The doctoral candidate submitting a justified application to withdraw from the programme.
  • The doctoral candidate not having completed their annual enrolment or applied for a temporary interruption.
  • The doctoral candidate not having formalised annual enrolment on the day after the end of the authorisation to temporarily interrupt or withdraw from the programme.
  • The doctoral candidate receiving a negative reassessment after the deadline set by the academic committee of the doctoral programme to remedy the deficiencies that led to a previous negative assessment.
  • The doctoral candidate having been the subject of disciplinary proceedings leading to their suspension or permanent exclusion from the UPC.
  • A refusal to authorise the extensions applied for, in accordance with the provisions of Section 3.3 of these regulations.
  • The doctoral candidate not having submitted the research plan in the period established in Section 8.2 of these regulations.
  • The maximum period of study for the doctoral degree having ended, in accordance with the provisions of Section 3.4 of these regulations.

Dismissal from the programme means that the doctoral candidate cannot continue studying at the UPC and that their academic record will be closed. This notwithstanding, they may apply to the academic committee of the programme for readmission, and the committee must reevaluate the candidate in accordance with the criteria established in the regulations.

A doctoral candidate who has been dismissed due to having exceeded the time limit for completing doctoral studies or due to an unsatisfactory assessment may not be Academic Regulations for Doctoral Studies Universitat Politècnica de Catalunya Page 17 of 33 admitted to the same doctoral programme until at least two years have elapsed from the date of dismissal, as provided for in sections 3.4 and 9.2 of these regulations.

Legal framework

Organization

COORDINATOR:
ACADEMIC COMMISSION OF THE PROGRAM:
Other Universities:

Universitat Autònoma de Barcelona

University of Girona

University of Lleida

University of Vic–Central University of Catalonia

Universitat Oberta de Catalunya

Universitat Rovira i Virgili (2021)

University of Barcelona (2021)


STRUCTURAL UNITS:
  • School of Mathematics and Statistics (PROMOTORA)
  • Barcelona Supercomputing Center-Centro Nacional de Supercomputación
  • Department of Automatic Control
  • Department of Chemical Engineering
  • Department of Civil and Environmental Engineering
  • Department of Computer Science
  • Department of Mathematics
  • Department of Physics
  • Department of Statistics and Operations Research
CONTACT:

School of Mathematics and Statistics (FME)
C/ Pau Gargallo, 14
08028 Barcelona

Tel.: 934 015 861

E-mail: gestio.doctorat.bioinformatica@upc.edu


Access, admission and registration

Access profile

Students must have adequate knowledge of the concepts and basic tools needed to carry out competitively funded research in the field of bioinformatics. Therefore, the main entry route to the programme is via a research-oriented master's degree in a discipline that is relevant to the field of bioinformatics, and priority will be given to applicants with this background.

There is one alternative entry route. Students who have not completed a master's degree but have completed a bachelor's degree in a discipline relevant to bioinformatics that carries at least 300 ECTS credits but does not include research training credits may be admitted to the programme on the condition that they complete, in their first year, 30 ECTS credits corresponding to subjects included on a master’s degree in bioinformatics taught at one of the universities involved in the programme.

The language of instruction for the programme is English. Students must therefore demonstrate a level of competence in English equivalent to Level B2 (upper intermediate) of the Common European Framework of Reference for Languages. If an applicant cannot provide certification of their level of English, this point will be assessed by the Selection and Progress Review Panel during the admission interview.

Access requirements

As a rule, applicants must hold a Spanish bachelor's degree or equivalent and a Spanish master's degree or equivalent, provided they have completed a minimum of 300 ECTS credits on the two degrees (Royal Decree 43/2015, of 2 February).

Applicants who meet one or more of the following conditions are also eligible for admission:

a) Holders of official Spanish degrees or equivalent Spanish qualifications, provided they have passed 300 ECTS credits in total and they can prove they have reached Level 3 in the Spanish Qualifications Framework for Higher Education.
b) Holders of degrees awarded in foreign education systems in the European Higher Education Area (EHEA), which do not require homologation, who can prove that they have reached Level 7 in the European Qualifications Framework, provided the degree makes the holder eligible for admission to doctoral studies in the country in which it was awarded.
c) Holders of degrees awarded in a country that does not belong to the EHEA, which do not require homologation, on the condition that the University is able to verify that the degree is of a level equivalent to that of official university master's degrees in Spain and that it makes the holder eligible for admission to doctoral studies in the country in which it was awarded.
d) Holders of another doctoral degree.
e) Holders of an official university qualification who, having been awarded a post as a trainee in the entrance examination for specialised medical training, have successfully completed at least two years of training leading to an official degree in a health sciences specialisation.

Note 1: Regulations for access to doctoral studies for individuals with degrees in bachelor's, engineering, or architecture under the system prior to the implementation of the EHEA (CG 47/02 2014).

Note 2: Agreement number 64/2014 of the Governing Council approving the procedure and criteria for assessing the academic requirements for admission to doctoral studies with non-homologated foreign degrees (CG 25/03 2014).

Legal framework

Admission criteria and merits assessment

1. Suitability of the applicant's bachelor's and master's degree (20%). The highest score on this point will be given to students who have completed a bachelor's or master's degree in bioinformatics. In other cases, consideration will be given to the research area that the applicant is seeking admission to.

2. Academic record for bachelor's and master's studies (45%). For this point, the Selection and Progress Review Panel will consider whether the applicant's academic record is competitive enough to obtain a predoctoral grant. If it is not, the applicant may only be admitted if a thesis supervisor who can provide some other type of predoctoral contract (covered by a project budget, for example) is proposed by the applicant or can be assigned by the programme.

3. A covering letter (max. 2 pages) in which the applicant explains why they wish to undertake doctoral studies in this programme, provides information on their academic background, and indicates which research area of the doctoral programme they are seeking admission to. Applicants may also propose a thesis supervisor if they deem this appropriate (10%).

4. Interview (15%). The interview will be conducted in English and will serve as a means of assessing the applicant's conversational skills in this language. It will also provide an opportunity for applicants to ask any questions they have or request additional information about the curriculum and objectives of the programme.

5. Additional academic activities: published research papers and conference papers (10%).

Training complements

The main entry route to the programme is via a research-oriented master's degree in a discipline that is relevant to the field bioinformatics. Priority will be given to applicants with this background. Students with this background will not need to take any compulsory bridging courses. However, the academic committee for the programme, in agreement with a student's tutors and thesis supervisor, may recommend optional bridging courses according to their academic background and chosen research area.

Students who have not completed a master's degree but have completed a bachelor's degree in a discipline relevant to bioinformatics that carries at least 300 ECTS credits but does not include research training credits may be admitted to the programme on the condition that they complete, in their first year, 30 ECTS credits corresponding to subjects included on a master's degree in bioinformatics taught at one of the universities involved in the programme. The content of the 30 ECTS credits will be decided by the thesis supervisor but must also be approved by the tutors and the academic committee.

Monitoring and evaluation of the doctoral student

Procedure for the preparation and defense of the research plan

Doctoral candidates must submit a research plan, which will be included in their doctoral student activity report, before the end of the first year. The plan may be improved over the course of the doctoral degree. It must be endorsed by the tutor and the supervisor, and it must include the method that is to be followed and the aims of the research.

At least one of these annual assessments will include a public presentation and defence of the research plan and work done before a committee composed of three doctoral degree holders, which will be conducted in the manner determined by each academic committee. The examination committee awards a Pass or Fail mark. A Pass mark is a prerequisite for continuing on the doctoral programme. Doctoral candidates awarded a Fail mark must submit a new research plan for assessment by the academic committee of the doctoral programme within six months.

The committee assesses the research plan every year, in addition to all of the other activities in the doctoral student activity report. Doctoral candidates who are awarded two consecutive Fail marks for the research plan will be obliged to definitely withdraw from the programme.

If they change the subject of their thesis, they must submit a new research plan.

Formation activities

Activity: Development of skills related to communication and dissemination of research – basic level (compulsory)
Hours: 36
Description:
Each of the selection and progress review panels for the programme (one per intake year; see Section 3.2) will organise annual progress review sessions that bring together doctoral students who were admitted to the programme in the same year. These sessions will also be used to develop students' research communication skills, which will be given particular attention during student presentations.

Activity: Attendance of working doctoral groups (compulsory)
Hours: 48
Description:
Each year, the doctoral programme will organise a one-day scientific workshop. Doctoral students must participate in at least two of these workshops, at which they will present a poster. The aim of the workshops will be to present, examine, share and discuss the state of the thesis research process in its initial, middle and final stages. Sessions will always be organised at three levels:
Initial: Conceptual approaches and complete research plan
Middle: Methodologies applied and methodological problems to be solved
Final: Expected results and results already achieved.
The workshops will follow a standard format, with oral presentations and two poster sessions (morning and afternoon). Workshops will be conducted in the language of instruction for the programme (English). Doctoral students must send summaries to the academic committee in advance. Based on these submissions, students will be selected to give 20-minute talks (with an additional 10 minutes for discussion) for each of the three levels indicated above.
This activity allows students to share experiences at three crucial points in their training process and gives the coordinator of the doctoral programme a clear idea of the direction, level and pace of their research.

Activity: Attendance of seminars or lectures given by experts in the area of knowledge (compulsory)
Hours: 9
Description:
The doctoral programme will organise a series of scientific seminars. A seminar will be held about once every two months (four per academic year) with the aim of improving doctoral students' knowledge of topics related to their thesis research. Doctoral students must attend at least three of these seminars each academic year for three years. Seminars will focus on topics covered by the programme and will be taught by internationally renowned researchers.

Activity: Presentation (poster or oral) at a national or international conference (compulsory)
Hours: 100
Description:
Presenting one's research and engaging in a discussion before audience members who are knowledgeable about the topic presented is one of the most effective ways to learn and improve one's research activity. Giving a presentation of this kind at an international conference that focuses specifically on the subject area of a doctoral student's thesis and is attended by researchers with a strong reputation in the relevant field of study is a crucial test and milestone for future researchers nearing the end of their academic training.
For this reason, the organisers of the doctoral programme propose that students participate in a scientific meeting (workshop or international conference) where they can present the results of their research and receive input and feedback from renowned researchers specialising in their field. These events also provide students with an opportunity to take part in discussions and provide input on significant issues in their subject area.
Given the highly specialised nature of academic events of this kind, students must be at an advanced stage of their thesis work to undertake this activity. This activity will be supervised and oriented by the student's thesis supervisor or tutors.

Activity: Writing of a research paper for submission to a high-impact scientific journal (compulsory)
Hours: 500
Description:
Students' most representative results will be presented in the form of a scientific paper.
In the process of producing a doctoral thesis, working intensively on key skills in formal and content-focused contexts is an experience that helps students optimise their scientific activity within the framework of the international research community. This activity also plays an important role in developing and training future researchers. It is essential that students understand the process, mechanisms, tools, expository and formal approaches and requirements that generally apply to the publication of research papers in indexed journals.
Given that papers are often the main tool for contemporary research, we believe it is vitally important that, before obtaining a doctoral degree, students gain experience in this area by writing at least one scientific paper for publication in an indexed journal.
This activity will be carried out when students are nearing completion of their experimental work and have obtained results that can form the basis of a scientific publication.

Activity: Research stays at public or private centres in Spain or abroad (optional)
Hours: 490 (3 months)
Description:
To be awarded an International Doctorate mention, during the training period required to earn a doctoral degree, students must complete a period of mobility of at least three months at a well-regarded higher education institution or research centre outside Spain and take courses or do research work there. The period of mobility and the activities carried out must be vouched for by the thesis supervisor, authorised by the academic committee and recorded on the doctoral student activity report. The required period of study may be non-continuous provided that the total time is at least three months and that all of this time is spent at the same institution. The training period starts when a student is admitted and ends when they are awarded a doctoral degree. Although periods of international mobility are optional, the programme will provide incentives so that the majority of doctoral students participate in this activity.

Procedure for assignment of tutor and thesis director

The academic committee of the doctoral programme assigns a thesis supervisor to each doctoral candidate when they are admitted or enrol for the first time, taking account of the thesis supervision commitment referred to in the admission decision.

The thesis supervisor will ensure that training activities carried out by the doctoral candidate are coherent and suitable, and that the topic of the candidate’s doctoral thesis will have an impact and make a novel contribution to knowledge in the relevant field. The thesis supervisor will also guide the doctoral candidate in planning the thesis and, if necessary, tailoring it to any other projects or activities undertaken. The thesis supervisor will generally be a UPC professor or researcher who holds a doctoral degree and has documented research experience. This includes PhD-holding staff at associated schools (as determined by the Governing Council) and UPC-affiliated research institutes (in accordance with corresponding collaboration and affiliation agreements). When thesis supervisors are UPC staff members, they also act as the doctoral candidate’s tutor.

PhD holders who do not meet these criteria (as a result of their contractual relationship or the nature of the institution to which they are attached) must be approved by the UPC Doctoral School's Standing Committee in order to participate in a doctoral programme as researchers with documented research experience.

The academic committee of the doctoral programme may approve the appointment of a PhD-holding expert who is not a UPC staff member as a candidate’s thesis supervisor. In such cases, the prior authorisation of the UPC Doctoral School's Standing Committee is required. A UPC staff member who holds a doctoral degree and has documented research experience must also be proposed to act as a co-supervisor, or as the doctoral candidate’s tutor if one has not been assigned.

A thesis supervisor may step down from this role if there are justified reasons (recognised as valid by the committee) for doing so. If this occurs, the academic committee of the doctoral programme will assign the doctoral candidate a new thesis supervisor.

Provided there are justified reasons for doing so, and after hearing any relevant input from the doctoral candidate, the academic committee of the doctoral programme may assign a new thesis supervisor at any time during the period of doctoral study.

If there are academic reasons for doing so (an interdisciplinary topic, joint or international programmes, etc.) and the academic committee of the programme gives its approval, an additional thesis supervisor may be assigned. Supervisors and co-supervisors have the same responsibilities and academic recognition.

The maximum number of supervisors of a doctoral thesis is two: a supervisor and a co-supervisor.

For theses carried out under a cotutelle agreement or as part of an Industrial Doctorate, if necessary and if the agreement foresees it this maximum number of supervisors may not apply. This notwithstanding, the maximum number of supervisors belonging to the UPC is two.

More information at the PhD theses section

Permanence

The maximum period of study for full-time doctoral studies is four years, counted from the date of first enrolment in the relevant programme until the date on which the doctoral thesis is deposited. The academic committee of the doctoral programme may authorise a doctoral candidate to pursue doctoral studies on a part-time basis. In this case, the maximum period of study is seven years from the date of first enrolment in the programme until the date on which the doctoral thesis is deposited. To calculate these periods, the date of deposit is considered to be the date on which the thesis is made publicly available for review.

If a doctoral candidate has a degree of disability equal to or greater than 33%, the maximum period of study is six years for full-time students and nine years for part-time students.

If a doctoral candidate has not applied to deposit their thesis before the expiry of the deadlines specified in the previous section, the academic committee of the doctoral programme may, at the request of the doctoral candidate, authorise an extension of this deadline of one year under the conditions specified for the doctoral programme in question.

Dismissal from the doctoral programme
A doctoral candidate may be dismissed from a doctoral programme for the following reasons:

  • The doctoral candidate submitting a justified application to withdraw from the programme.
  • The doctoral candidate not having completed their annual enrolment or applied for a temporary interruption.
  • The doctoral candidate not having formalised annual enrolment on the day after the end of the authorisation to temporarily interrupt or withdraw from the programme.
  • The doctoral candidate receiving a negative reassessment after the deadline set by the academic committee of the doctoral programme to remedy the deficiencies that led to a previous negative assessment.
  • The doctoral candidate having been the subject of disciplinary proceedings leading to their suspension or permanent exclusion from the UPC.
  • A refusal to authorise the extensions applied for, in accordance with the provisions of Section 3.3 of these regulations.
  • The doctoral candidate not having submitted the research plan in the period established in Section 8.2 of these regulations.
  • The maximum period of study for the doctoral degree having ended, in accordance with the provisions of Section 3.4 of these regulations.

Dismissal from the programme means that the doctoral candidate cannot continue studying at the UPC and that their academic record will be closed. This notwithstanding, they may apply to the academic committee of the programme for readmission, and the committee must reevaluate the candidate in accordance with the criteria established in the regulations.

A doctoral candidate who has been dismissed due to having exceeded the time limit for completing doctoral studies or due to an unsatisfactory assessment may not be Academic Regulations for Doctoral Studies Universitat Politècnica de Catalunya Page 17 of 33 admitted to the same doctoral programme until at least two years have elapsed from the date of dismissal, as provided for in sections 3.4 and 9.2 of these regulations.

Legal framework

Learning resources

Specific libraries in the field of the doctoral programme that are broad and well stocked with materials in a range of formats and access to the databases required by students on the programme (CAB, Agrícola, Agris, Scopus, Web of Knowledge, etc.). Students can access these databases from any location at the respective universities. The libraries have long opening hours and a wide range of lending services that include laptops and tablets. The libraries give courses on demand on accessing and using sources of information and are part of a consortium with the rest of the libraries of Catalan universities, so they can manage loans of documents held at any of the libraries.

Scientific and Technical Services. The University has a catalogue of scientific and technical services. The head of the Scientific and Technical Services is an academic who has first-hand knowledge of the services and acts as a scientific adviser. There is also the specialised staff required to provide the service. The Scientific and Technical Services can be used by doctoral candidates to obtain results for their research, when its methodological complexity lies beyond the scope of their doctoral topic, or as a tool in their training, when they participate in preparing samples for analysis.
Doctoral candidates write their doctoral theses in the framework of a national or international competitive research project. Those who are involved in international projects have partners at foreign institutions in Europe and other continents. In these cases, internationalisation is part of the essence of the thesis, and students visit or stay at the institutions of the other partners in the project and receive other doctoral candidates or researchers for short stays or symposia and internal meetings.

Doctoral Theses

List of authorized thesis for defense

  • CABRERA PASADAS, MÓNICA: Exploring the impact of p53 activation on spatio-temporal genome topology
    Author: CABRERA PASADAS, MÓNICA
    Thesis file: (contact the Doctoral School to confirm you have a valid doctoral degree and to get the link to the thesis)
    Programme: DOCTORAL DEGREE IN BIOINFORMATICS
    Department: Department of Statistics and Operations Research (EIO)
    Mode: Normal
    Deposit date: 27/10/2023
    Reading date: 09/07/2024
    Reading time: 10:00
    Reading place: Sala d'Actes de l'FME, Edifici U, Campus Sud
    Thesis director: JAVIERRE MARTINEZ, BIOLA M | VALENCIA HERRERA, ALFONSO
    Committee:
         PRESIDENT: MARTI-RENOM, MARC A
         SECRETARI: DELICADO USEROS, PEDRO FRANCISCO
         VOCAL: RAMOS RODRIGUEZ, MIREIA
         VOCAL NO PRESENCIAL: STIK, GREGOIRE
         VOCAL NO PRESENCIAL: GÓMEZ MELIS, GUADALUPE
    Thesis abstract: The year I started this Ph.D. (2019) was the 40th anniversary of the discovery of p53 and the 30th anniversary of its characterization as a tumor suppressor. Approximately, half of all human cancers carry mutations or deletions of the p53 gene, while the other half have disruptions to the p53 signaling pathway. Nevertheless, despite decades of extensive research the precise molecular mechanisms underpinning p53-mediated gene regulation and its tumor-suppressive efficacy remain partially elucidated.Under non genotoxic or oncogenic stressed conditions, the MDM2 protein promotes ubiquitination and proteasome-mediated degradation of p53 maintaining low cellular levels. However, upon encountering cellular stress, the p53-MDM2 interaction is disrupted leading to p53 accumulation and activation. Once active, p53 promotes critical cell fate decisions such as cell cycle arrest, apoptosis, or senescence by transactivating an array of target genes, leading to effective tumor regression. Consequently, the loss of p53 functionality is intrinsically linked to cancer susceptibility, rendering p53 an enticing candidate for anti-cancer therapeutic interventions. Cis-regulatory elements master gene expression through the control of transcription in temporal and spatial dimensions. However, the mechanisms by which p53 engages the genome in the context of 3D chromatin to activate transcription are not well understood ¿the interplay between p53 and 3D genome organization has remained unexplored to date.This doctoral thesis investigates p53s ability to reconfigure the genome and govern transcriptional regulation by inducing alterations in the temporal and spatial genome structure. It is the hypothesis of this dissertation that p53 exerts its influence by modulating physical connections between regulatory elements, enhancers, and gene promoters via the manipulation of DNA loops.To rigorously assess this proposition, a comprehensive investigation into the potential ramifications of p53 activation in HCT116 cell lines achieved through pharmacologically inhibiting MDM2 with Nutlin-3a drug has been outlined. This approach synergistically integrates diverse genomic datasets, encompassing Hi-C, Promoter Capture Hi-C, RNA-seq, and ChIP-seq methodologies. The analysis unveils that p53 activation precipitates both direct and indirect modifications in genome architecture, manifesting within minutes of its induction. By deciphering the nexus between 3D genome organization and p53-driven transcriptional regulation, this thesis aspires to help in the unravel avenues for therapeutic intervention in the realm of cancer treatment.

Last update: 27/05/2024 04:45:20.

List of lodged theses

Last update: 27/05/2024 04:30:28.

List of defended theses by year

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Last update: 27/05/2024 05:00:40.

Theses related publications

AUTHOR:VILA I JULIÀ, GUILLEM
Title:Rational-Design of New Candidates Targeting Bak and Bombesin Receptors in Cancer
Reading date:22/11/2023
Director:PEREZ GONZALEZ, JUAN JESUS
Co-director:RUBIO MARTÍNEZ, JAIME
Mention:No mention
RELATED PUBLICATIONS
A step forward toward selective activation/inhibition of bak, a pro-apoptotic member of the Bcl-2 protein family: discovery of new prospective allosteric sites using molecular dynamics
Vila-Julià, G.; Perez, J.; Rubio-Martinez, J.
Journal of chemical information and modeling, ISSN: 1549-960X (JCR Impact Factor-2021: 6.162; Quartil: Q1)
Publication date: 01/01/2023
Journal article

Obrint els Ulls en l'Al·losterisme de la Proteïna Proapoptòtica Bak
1a Reunió de Química Teòrica i Computacional
Presentation date: 31/01/2023
Presentation of work at congresses

Establishing a Binding Model for Bombesin to Bombesin Receptors
Modeling Interactions in Biomolecules IX
Presentation date: 11/09/2023
Presentation of work at congresses

Research projects

START DATEEND DATEACTIVITYFINANCING ENTITY
01/12/202330/11/2026J-03162AGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/10/202330/09/2027Improving BiomEdical diagnosis through LIGHT-based technologies and machine learningCommission of European Communities
12/09/202330/06/2026Chips para arquitecturas avanzadas y sistemas fotónicosMIN DE ECONOMIA Y COMPETITIVIDAD
01/09/202331/08/2026Apoyo a la decisión en oftalmología basado en Machine Learning y aplicado a imágenes multi-modales de la retinaAGENCIA ESTATAL DE INVESTIGACION
01/05/202330/04/2026Towards a personalized medicine approach to psychological treatment for psychosisEuropean Commission
01/03/202330/09/2023Donació per a donar suport al Grup de Recerca B2slabARTIFICIAL INTELLIGENCE AUDITS & CE
01/01/202331/12/2024Aportacions de la genètica a la caracterització de una cohort de Medicina Personalitzada de PrecisióGENERALITAT DE CATALUNYA
01/01/202331/12/2025Xarxa R+D+I en Tecnologies de la Salut (Xartec Salut)AGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/01/202331/12/2025Hacia un enfoque de medicina personalizada para el tratamiento psicológico de la psicosisINSTITUTO DE SALUD CARLOS III
01/01/202331/12/2025Gestión clínica personalizada del paciente oncológico con insuficiencia renal agudaINSTITUTO DE SALUD CARLOS III
01/01/202331/12/2025Xarxa d’Innovació de Noves Tecnologies en Salut MentalAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/01/202331/12/2025HUB D'INNOVACIÓ PEDIÀTRICAFondo Europeo de Desarrollo Regional
01/01/202331/08/2025Grup de Sistemes Dinàmics de la UPC. Ajuts als grups de recerca (AGRUPS-2023).Universitat Politècnica de Catalunya
01/01/202331/08/2025Grup Recerca Acreditat SGR. Grup de Sistemes Dinàmics de la UPC (UPCDS)Agència de Gestió d'Ajuts Universitaris de Recerca
01/11/202231/10/2026Unite! University Network for Innovation, Technology and EngineeringEuropean Commission. Education Audiovisual and Culture Agency Executive Agency (Eacea)
01/09/202231/08/2025Métodos formales escalables para aplicaciones en entornos realesAGENCIA ESTATAL DE INVESTIGACION
01/09/202231/08/2025Invariant Manifolds, Hamiltonian systems and dynamics in Neuroscience, Epidemiology and AtmosphereAGENCIA ESTATAL DE INVESTIGACION
01/09/202231/08/2025Métodos y aplicaciones de aprendizaje profundo y superficial de fenotipos para análisis y predicción de datos biomédicos.AGENCIA ESTATAL DE INVESTIGACION
01/09/202231/08/2025Smart Health Ecosystem for managing Breathing Illnesses and Optimizing Sleep in patients with COPD, COVID and Sleep DisordersMICINN
27/07/202227/07/2022Monitoring sleeping disorders and system teherof
29/06/202229/06/2022Perfiles de biomarcadores genéticos para la aptitud para el deporte de resistencia
01/06/202231/05/2023Cribratge i seguiment del tractament per Hipertensió Arterial (HTA) en col·lectius d'alta vulnerabilitat amb problemes d’accés al sistema sanitariCentre de Cooperació per al Desenvolupament de la UPC
04/05/202204/05/2022Procedimiento de procesamiento de imágenes para la detección del glaucoma y productos de programa informático asociados
01/03/202201/04/2022Contrato de colaboració en Distrofias hereditarias de retina, osteogénesis imperfecta, dermatomiositis y síndrome de KabukiFUNDACIO PRIVADA PER A LA RECERCA I
01/01/202231/12/2025Semàntica de les paraules del català: teoria i aplicacions clíniques.Institut d'Estudis Catalans
01/01/202231/12/2025María de Maeztu Program for Centers and Units of Excellence in R&D (proyecto CEX2020-001084-M).Agencia Estatal de Investigación
01/01/202231/12/2025Centre de Recerca MatemàticaAgencia Estatal de Investigación
01/01/202231/12/2023Contrato de colaboración para la realización de una asesoría técnica del centro en los temas relacionados con las líneas de conocimiento del grupo B2SLab en análisis estadístico, bigdata y data miningUNIVERSAL DIAGNOSTICS SL
01/01/202231/12/2024Experimentos y análisis de datos para caracterizar y pronosticar el comportamiento de sistemas complejosAGENCIA ESTATAL DE INVESTIGACION
01/12/202101/12/2021CompARE
01/12/202131/01/2022Vocabulario, diccionario y aplicacionesTELEFONICA I + D, S.A.UNIP.
25/11/202131/12/2023CAIXAIMPULSE VALIDATE CI21-00186FUNDACIO LA CAIXA
01/09/202131/08/2024Análisis computacional del impacto de riesgos genéticos y clínicos en la señalización molecular y disfunciones electrofisiológicas en fibrilación auricular.AGENCIA ESTATAL DE INVESTIGACION
15/06/202115/06/2021CompAREdesign
14/05/202113/11/2022Dynamic evaluation of COVID-19 clinical states and their prognostic factors to improve the intra-hospital patient managementAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
30/04/202130/04/2024Ús de la intel·ligència artificial i la biologia de sistemes per a la diagnosi i l’avaluació de risc personalitzat per a les malalties renals hereditàries, centrat en la sndrome d’AlportLA FUNDACIÓ LA MARATÓ DE TV3
01/01/202131/12/2024Ampliación del contrato de colaboración para la identificación y diseño de pequeñas moléculas como nuevas cabezas de serie inhibidores de MAP quinasas y proteína RasAllinky Biopharma S.L.
01/01/202131/12/2021Aplicacions de la lingüística quantitativa en el català.Institut d'Estudis Catalans
01/01/202131/12/2023Planing the Future of R&I in European University Alliance UniteEuropean Commission
19/11/202018/11/2023Sistema de ventilación inteligente y detección del nivel de higienización de interiores (VIDA)Agència per la Competitivitat de l'Empresa (ACCIÓ)
01/11/202030/04/2022Convocatòria d'una beque d’iniciació a la recerca dins del grup de recerca B2SLab.EXHEUS, SL
01/09/202031/08/2023Programme européen de formation en industrie 4.0 dans le cadre de l'Université Européenne UNITE!Gobierno de Francia
15/08/202031/12/2022Xarxa R+D+I en Tecnologies de la Salut (XarTEC SALUT)AGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
15/07/202031/10/2021The goal of this project is to encapsulate the Quality Control as an in-house algorithm. The project is divided on to four different milestones.UNIVERSAL DIAGNOSTICS SL
15/07/202015/07/2021Disseny d’un formulari segur de registre, Generació estadística descriptiva senzilla de qüestionaris, Generació d’un dashboard.FUNDACIO PRIVADA PER A LA RECERCA I
13/07/202031/12/2023Platform of Epigenetic Classifiers for Childhood CAncer (PECA)LA FUNDACIÓ LA MARATÓ DE TV3
01/07/202031/12/2020Crowdsourced Obtention and Analytics of Data About the Crowding of Public Spaces for the Benefit of Public Transport and Mobility in CitiesEUROPEAN INST OF INNOV.& TECHNOL.
01/07/202031/12/2022Red de Innovación de Nuevas Tecnologías en Salud Mental (TECSAM)Fondos FEDER
01/06/202031/05/2023Generación Óptica de Armónicos en Materiales Estratégicos para la NanofotónicaAGENCIA ESTATAL DE INVESTIGACION
01/06/202029/02/2024Nuevos ligandos alostéricos del receptor acoplado a proteína G visual rodopsina y el mecanismo molecular de enfermedadesAGENCIA ESTATAL DE INVESTIGACION
01/06/202031/05/2024Geometría, Álgebra, Topología y Aplicaciones MultidisciplinaresAGENCIA ESTATAL DE INVESTIGACION
01/06/202030/09/2023Aprendizaje Automático para la Modelización de la Dinámica Molecular de las Proteinas GPCRAGENCIA ESTATAL DE INVESTIGACION
01/06/202031/05/2024Metodologías estadísticas para datos clínicos y ómicos y sus aplicaciones en ciencias de la saludAGENCIA ESTATAL DE INVESTIGACION
06/05/202006/09/2020Identificacion de inhibidores de la proteasa Mpro del virus COVID-19 por repovisionamiento de medicamentosINSTITUTO DE SALUD CARLOS III
03/03/202031/12/2022Hub d'Innovació PediàtricaFondos FEDER
01/03/202031/12/2022Centre de Recerca i Transferència en Salut Mental (CRETSAM)Fondos FEDER
01/03/202028/02/2021Systematization of the acquisition of data throughout Ecuador of the beneficiaries or potential beneficiaries through a digital platform that allows citizens to locate the sites where the physical-rhythmic and recreational activities are carried outCentre de Cooperació per al Desenvolupament , UPC
01/03/202028/02/2021Collaborative intelligence to improve clinical care in low-income countriesCentre de Cooperació per al Desenvolupament , UPC
01/01/202031/12/2021Red Temática de Cálculo Simbólico, Algebra computacional y AplicacionesMinisterio de Ciencia, Innovación y Universidades
01/12/201930/11/2021el projecte tracta de implementar un sistema intern de garantia de la qualitat a Russian-Tajik (Slavonic) UniversityRussian-Tajik Slavonic University
13/11/201931/12/2020HealthXCode - COLLIDER 2019FUNDACIO BARCELONA MOBILE WORLD CAP
01/11/201901/04/2020El proyecto consiste en el desarrollo de un sistema de clusterización/segmentación de pacientes con EPOC, según su grado de adherencia al plan terapéuticoPULSO EDICIONES, SL
01/11/201931/10/2022University Network for Innovation, Technology and EngineeringEuropean Commission
14/10/201931/12/2020Desarrollar un sistema automatizado de audiometría verbal. desarrollar un sistema de audiometría verbal con la capacidad de disponer de reconocimiento de voz automático.DEVIMETRIX, S.L.
01/10/201902/09/2021Desarrollo de un sistema de clusterización/segmentación de pacientes diabéticos tipo 2, según su adherencia al plan terapéuticoPULSO EDICIONES, SL
01/09/201931/08/2022Systemic University Change Towards Internationalisation for AcademiaCommission of European Communities
01/06/201931/12/2020Aprendizaje automático y análisis de datos para tecnologías fotónicas biomédicasAGENCIA ESTATAL DE INVESTIGACION
01/06/201931/05/2022TRaceo y ACompañamiento en el viaje con medios ITAGENCIA ESTATAL DE INVESTIGACION
17/05/201917/05/2019A computer implemented method, a system and computer programs for anomaly detection using network analysis
06/05/201931/01/2020SISTEMA BASAT EN SENSORS DE GAS PEL MONITORATGE I SEGURETAT DELS ANCIANS A CASAAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
12/04/201911/04/2022In silico modelling towards 3Rs paradigmFUND.I.INVEST.C.SALUT TRIAS I PUJOL
04/04/201931/10/2020Multiparametric MR approaches for non-invasive Gliobastoma therapy response follow-upCommission of European Communities
01/03/201928/02/2023Climate Advanced Forecasting of sub-seasonalCommission of European Communities
01/03/201928/02/2023Eines algorítmiques per a l'anàlisi de l'evolució temporal de pacients en els sistemes de salutAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/03/201928/02/2023Cognitive vergence captured by CMOS sensorsAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/03/201928/02/2020Adquisición de datos para optimizar la oferta de servicios, de promoción de la vida sana, entre los habitantes de zonas desfavorables de GuayaquilCentre de Cooperació per al Desenvolupament , UPC
01/03/201931/12/2023Evaluation of noninvasive indices for respiratory monitoring, focusing on the applicability at homeIMEC
27/02/201927/02/2021Impacte de la formació en l'Acadèmia de Ciències Mèdiques en termes d'indicadors de responsabilitat socialACADÈMIA CIÈNCIES MÈDIQUES
01/01/201931/12/2020RCO03080 Lingüística quantitativaInstitut d'Estudis Catalans
01/01/201930/09/2022Razonamiento Formal para Tecnologías Facilitadoras y EmergentesAGENCIA ESTATAL DE INVESTIGACION
01/01/201931/12/2021Sistemas dinámicos complejos y herramientas avanzadas de análisis de datosAGENCIA ESTATAL DE INVESTIGACION
01/01/201930/09/2022Dinámica Asociada a Conexiones entre Objetos Invariantes con Aplicaciones a la Neurociencia y la MecánicaAGENCIA ESTATAL DE INVESTIGACION
01/01/201931/12/2019Anàlisi estadístic,bigdata i data miningUNIVERSAL DIAGNOSTICS SL
01/01/201931/12/2021Development of novel mathematical and experimental methodologies to control neuronal activity and dissect spatio-temporal neuronal codesMinisterio de Ciencia, Innovación y Universidades
01/01/201931/12/2021Desarrollo de estrategias ómicas para revelar el pangenoma de especies, la coevolución de los virus y la adaptación en los extremos de concentración salinaMinisterio de Ciencia e Innovación
01/01/201931/12/2022INtegrating Magnetic Resonance SPectroscopy and Multimodal Imaging for Research and Education in MEDicineEuropean Commission
01/01/201931/12/2019EIT Urban Mobility Start-up phaseEIT Urban Mobility
01/01/201930/09/2022Smart health ecosystem (tools, apps and devices) for personalized medicine and Healthcare in REspiratory diseases and Sleep disordersFondos FEDER; Ministerio de Ciencia, Innovación y Universidades
15/09/200930/11/2026DONACIONS A LA RECERCACLIENTS DIVERSOS
29/04/200401/12/2021ASSAJOS CLÍNICS VIH/SIDAFUNDACIÓ LLUITA CONTRA LA SIDA (duplicat 0000003656)

Teaching staff and research groups

Research projects

START DATEEND DATEACTIVITYFINANCING ENTITY
01/12/202330/11/2026J-03162AGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/10/202330/09/2027Improving BiomEdical diagnosis through LIGHT-based technologies and machine learningCommission of European Communities
12/09/202330/06/2026Chips para arquitecturas avanzadas y sistemas fotónicosMIN DE ECONOMIA Y COMPETITIVIDAD
01/09/202331/08/2026Apoyo a la decisión en oftalmología basado en Machine Learning y aplicado a imágenes multi-modales de la retinaAGENCIA ESTATAL DE INVESTIGACION
01/05/202330/04/2026Towards a personalized medicine approach to psychological treatment for psychosisEuropean Commission
01/03/202330/09/2023Donació per a donar suport al Grup de Recerca B2slabARTIFICIAL INTELLIGENCE AUDITS & CE
01/01/202331/12/2024Aportacions de la genètica a la caracterització de una cohort de Medicina Personalitzada de PrecisióGENERALITAT DE CATALUNYA
01/01/202331/12/2025Xarxa R+D+I en Tecnologies de la Salut (Xartec Salut)AGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/01/202331/12/2025Hacia un enfoque de medicina personalizada para el tratamiento psicológico de la psicosisINSTITUTO DE SALUD CARLOS III
01/01/202331/12/2025Gestión clínica personalizada del paciente oncológico con insuficiencia renal agudaINSTITUTO DE SALUD CARLOS III
01/01/202331/12/2025Xarxa d’Innovació de Noves Tecnologies en Salut MentalAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/01/202331/12/2025HUB D'INNOVACIÓ PEDIÀTRICAFondo Europeo de Desarrollo Regional
01/01/202331/08/2025Grup de Sistemes Dinàmics de la UPC. Ajuts als grups de recerca (AGRUPS-2023).Universitat Politècnica de Catalunya
01/01/202331/08/2025Grup Recerca Acreditat SGR. Grup de Sistemes Dinàmics de la UPC (UPCDS)Agència de Gestió d'Ajuts Universitaris de Recerca
01/11/202231/10/2026Unite! University Network for Innovation, Technology and EngineeringEuropean Commission. Education Audiovisual and Culture Agency Executive Agency (Eacea)
01/09/202231/08/2025Métodos formales escalables para aplicaciones en entornos realesAGENCIA ESTATAL DE INVESTIGACION
01/09/202231/08/2025Invariant Manifolds, Hamiltonian systems and dynamics in Neuroscience, Epidemiology and AtmosphereAGENCIA ESTATAL DE INVESTIGACION
01/09/202231/08/2025Métodos y aplicaciones de aprendizaje profundo y superficial de fenotipos para análisis y predicción de datos biomédicos.AGENCIA ESTATAL DE INVESTIGACION
01/09/202231/08/2025Smart Health Ecosystem for managing Breathing Illnesses and Optimizing Sleep in patients with COPD, COVID and Sleep DisordersMICINN
27/07/202227/07/2022Monitoring sleeping disorders and system teherof
29/06/202229/06/2022Perfiles de biomarcadores genéticos para la aptitud para el deporte de resistencia
01/06/202231/05/2023Cribratge i seguiment del tractament per Hipertensió Arterial (HTA) en col·lectius d'alta vulnerabilitat amb problemes d’accés al sistema sanitariCentre de Cooperació per al Desenvolupament de la UPC
04/05/202204/05/2022Procedimiento de procesamiento de imágenes para la detección del glaucoma y productos de programa informático asociados
01/03/202201/04/2022Contrato de colaboració en Distrofias hereditarias de retina, osteogénesis imperfecta, dermatomiositis y síndrome de KabukiFUNDACIO PRIVADA PER A LA RECERCA I
01/01/202231/12/2025Semàntica de les paraules del català: teoria i aplicacions clíniques.Institut d'Estudis Catalans
01/01/202231/12/2025María de Maeztu Program for Centers and Units of Excellence in R&D (proyecto CEX2020-001084-M).Agencia Estatal de Investigación
01/01/202231/12/2025Centre de Recerca MatemàticaAgencia Estatal de Investigación
01/01/202231/12/2023Contrato de colaboración para la realización de una asesoría técnica del centro en los temas relacionados con las líneas de conocimiento del grupo B2SLab en análisis estadístico, bigdata y data miningUNIVERSAL DIAGNOSTICS SL
01/01/202231/12/2024Experimentos y análisis de datos para caracterizar y pronosticar el comportamiento de sistemas complejosAGENCIA ESTATAL DE INVESTIGACION
01/12/202101/12/2021CompARE
01/12/202131/01/2022Vocabulario, diccionario y aplicacionesTELEFONICA I + D, S.A.UNIP.
25/11/202131/12/2023CAIXAIMPULSE VALIDATE CI21-00186FUNDACIO LA CAIXA
01/09/202131/08/2024Análisis computacional del impacto de riesgos genéticos y clínicos en la señalización molecular y disfunciones electrofisiológicas en fibrilación auricular.AGENCIA ESTATAL DE INVESTIGACION
15/06/202115/06/2021CompAREdesign
14/05/202113/11/2022Dynamic evaluation of COVID-19 clinical states and their prognostic factors to improve the intra-hospital patient managementAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
30/04/202130/04/2024Ús de la intel·ligència artificial i la biologia de sistemes per a la diagnosi i l’avaluació de risc personalitzat per a les malalties renals hereditàries, centrat en la sndrome d’AlportLA FUNDACIÓ LA MARATÓ DE TV3
01/01/202131/12/2024Ampliación del contrato de colaboración para la identificación y diseño de pequeñas moléculas como nuevas cabezas de serie inhibidores de MAP quinasas y proteína RasAllinky Biopharma S.L.
01/01/202131/12/2021Aplicacions de la lingüística quantitativa en el català.Institut d'Estudis Catalans
01/01/202131/12/2023Planing the Future of R&I in European University Alliance UniteEuropean Commission
19/11/202018/11/2023Sistema de ventilación inteligente y detección del nivel de higienización de interiores (VIDA)Agència per la Competitivitat de l'Empresa (ACCIÓ)
01/11/202030/04/2022Convocatòria d'una beque d’iniciació a la recerca dins del grup de recerca B2SLab.EXHEUS, SL
01/09/202031/08/2023Programme européen de formation en industrie 4.0 dans le cadre de l'Université Européenne UNITE!Gobierno de Francia
15/08/202031/12/2022Xarxa R+D+I en Tecnologies de la Salut (XarTEC SALUT)AGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
15/07/202031/10/2021The goal of this project is to encapsulate the Quality Control as an in-house algorithm. The project is divided on to four different milestones.UNIVERSAL DIAGNOSTICS SL
15/07/202015/07/2021Disseny d’un formulari segur de registre, Generació estadística descriptiva senzilla de qüestionaris, Generació d’un dashboard.FUNDACIO PRIVADA PER A LA RECERCA I
13/07/202031/12/2023Platform of Epigenetic Classifiers for Childhood CAncer (PECA)LA FUNDACIÓ LA MARATÓ DE TV3
01/07/202031/12/2020Crowdsourced Obtention and Analytics of Data About the Crowding of Public Spaces for the Benefit of Public Transport and Mobility in CitiesEUROPEAN INST OF INNOV.& TECHNOL.
01/07/202031/12/2022Red de Innovación de Nuevas Tecnologías en Salud Mental (TECSAM)Fondos FEDER
01/06/202031/05/2023Generación Óptica de Armónicos en Materiales Estratégicos para la NanofotónicaAGENCIA ESTATAL DE INVESTIGACION
01/06/202029/02/2024Nuevos ligandos alostéricos del receptor acoplado a proteína G visual rodopsina y el mecanismo molecular de enfermedadesAGENCIA ESTATAL DE INVESTIGACION
01/06/202031/05/2024Geometría, Álgebra, Topología y Aplicaciones MultidisciplinaresAGENCIA ESTATAL DE INVESTIGACION
01/06/202030/09/2023Aprendizaje Automático para la Modelización de la Dinámica Molecular de las Proteinas GPCRAGENCIA ESTATAL DE INVESTIGACION
01/06/202031/05/2024Metodologías estadísticas para datos clínicos y ómicos y sus aplicaciones en ciencias de la saludAGENCIA ESTATAL DE INVESTIGACION
06/05/202006/09/2020Identificacion de inhibidores de la proteasa Mpro del virus COVID-19 por repovisionamiento de medicamentosINSTITUTO DE SALUD CARLOS III
03/03/202031/12/2022Hub d'Innovació PediàtricaFondos FEDER
01/03/202031/12/2022Centre de Recerca i Transferència en Salut Mental (CRETSAM)Fondos FEDER
01/03/202028/02/2021Systematization of the acquisition of data throughout Ecuador of the beneficiaries or potential beneficiaries through a digital platform that allows citizens to locate the sites where the physical-rhythmic and recreational activities are carried outCentre de Cooperació per al Desenvolupament , UPC
01/03/202028/02/2021Collaborative intelligence to improve clinical care in low-income countriesCentre de Cooperació per al Desenvolupament , UPC
01/01/202031/12/2021Red Temática de Cálculo Simbólico, Algebra computacional y AplicacionesMinisterio de Ciencia, Innovación y Universidades
01/12/201930/11/2021el projecte tracta de implementar un sistema intern de garantia de la qualitat a Russian-Tajik (Slavonic) UniversityRussian-Tajik Slavonic University
13/11/201931/12/2020HealthXCode - COLLIDER 2019FUNDACIO BARCELONA MOBILE WORLD CAP
01/11/201901/04/2020El proyecto consiste en el desarrollo de un sistema de clusterización/segmentación de pacientes con EPOC, según su grado de adherencia al plan terapéuticoPULSO EDICIONES, SL
01/11/201931/10/2022University Network for Innovation, Technology and EngineeringEuropean Commission
14/10/201931/12/2020Desarrollar un sistema automatizado de audiometría verbal. desarrollar un sistema de audiometría verbal con la capacidad de disponer de reconocimiento de voz automático.DEVIMETRIX, S.L.
01/10/201902/09/2021Desarrollo de un sistema de clusterización/segmentación de pacientes diabéticos tipo 2, según su adherencia al plan terapéuticoPULSO EDICIONES, SL
01/09/201931/08/2022Systemic University Change Towards Internationalisation for AcademiaCommission of European Communities
01/06/201931/12/2020Aprendizaje automático y análisis de datos para tecnologías fotónicas biomédicasAGENCIA ESTATAL DE INVESTIGACION
01/06/201931/05/2022TRaceo y ACompañamiento en el viaje con medios ITAGENCIA ESTATAL DE INVESTIGACION
17/05/201917/05/2019A computer implemented method, a system and computer programs for anomaly detection using network analysis
06/05/201931/01/2020SISTEMA BASAT EN SENSORS DE GAS PEL MONITORATGE I SEGURETAT DELS ANCIANS A CASAAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
12/04/201911/04/2022In silico modelling towards 3Rs paradigmFUND.I.INVEST.C.SALUT TRIAS I PUJOL
04/04/201931/10/2020Multiparametric MR approaches for non-invasive Gliobastoma therapy response follow-upCommission of European Communities
01/03/201928/02/2023Climate Advanced Forecasting of sub-seasonalCommission of European Communities
01/03/201928/02/2023Eines algorítmiques per a l'anàlisi de l'evolució temporal de pacients en els sistemes de salutAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/03/201928/02/2023Cognitive vergence captured by CMOS sensorsAGAUR. Agència de Gestió d'Ajuts Universitaris i de Recerca
01/03/201928/02/2020Adquisición de datos para optimizar la oferta de servicios, de promoción de la vida sana, entre los habitantes de zonas desfavorables de GuayaquilCentre de Cooperació per al Desenvolupament , UPC
01/03/201931/12/2023Evaluation of noninvasive indices for respiratory monitoring, focusing on the applicability at homeIMEC
27/02/201927/02/2021Impacte de la formació en l'Acadèmia de Ciències Mèdiques en termes d'indicadors de responsabilitat socialACADÈMIA CIÈNCIES MÈDIQUES
01/01/201931/12/2020RCO03080 Lingüística quantitativaInstitut d'Estudis Catalans
01/01/201930/09/2022Razonamiento Formal para Tecnologías Facilitadoras y EmergentesAGENCIA ESTATAL DE INVESTIGACION
01/01/201931/12/2021Sistemas dinámicos complejos y herramientas avanzadas de análisis de datosAGENCIA ESTATAL DE INVESTIGACION
01/01/201930/09/2022Dinámica Asociada a Conexiones entre Objetos Invariantes con Aplicaciones a la Neurociencia y la MecánicaAGENCIA ESTATAL DE INVESTIGACION
01/01/201931/12/2019Anàlisi estadístic,bigdata i data miningUNIVERSAL DIAGNOSTICS SL
01/01/201931/12/2021Development of novel mathematical and experimental methodologies to control neuronal activity and dissect spatio-temporal neuronal codesMinisterio de Ciencia, Innovación y Universidades
01/01/201931/12/2021Desarrollo de estrategias ómicas para revelar el pangenoma de especies, la coevolución de los virus y la adaptación en los extremos de concentración salinaMinisterio de Ciencia e Innovación
01/01/201931/12/2022INtegrating Magnetic Resonance SPectroscopy and Multimodal Imaging for Research and Education in MEDicineEuropean Commission
01/01/201931/12/2019EIT Urban Mobility Start-up phaseEIT Urban Mobility
01/01/201930/09/2022Smart health ecosystem (tools, apps and devices) for personalized medicine and Healthcare in REspiratory diseases and Sleep disordersFondos FEDER; Ministerio de Ciencia, Innovación y Universidades
15/09/200930/11/2026DONACIONS A LA RECERCACLIENTS DIVERSOS
29/04/200401/12/2021ASSAJOS CLÍNICS VIH/SIDAFUNDACIÓ LLUITA CONTRA LA SIDA (duplicat 0000003656)

Quality

The Validation, Monitoring, Modification and Accreditation Framework (VSMA Framework) for official degrees ties the quality assurance processes (validation, monitoring, modification and accreditation) carried out over the lifetime of a course to two objectives—the goal of establishing coherent links between these processes, and that of achieving greater efficiency in their management—all with the overarching aim of improving programmes.

Validation

        Registry of Universities, Centers and Degrees (RUCT)

        Quality section on the home university website

        Indicators